BEBOT'S GATEWAY TO THE BRAIN - WHY AN INHALER?
BeBot is designed to receive data from the brain, to alter patterns in our subconscience and to regulate cognitive processes. We are aware of the potential danger this intervention entails. Therefore, we are careful to focus in our BeBot‘s design solely on favourable applications. We aim to facilitate dietary changes and assist people with specific ailments (diabetes, intolerances, cancer etc. … ) In particular, we are interested in concepts to breach the blood-brain barrier for diagnostic and therapeutic purposes.
„The connection between the nasal cavity and the CNS (central nervous system) by the olfactory neurones has been investigated extensively with regard to its feasibility to serve as a direct drug transport route to the cerebrospinal fluid and brain. It has been proved that neurotrophine, neuropeptide, insulin, cytokines and even DNA could enter CNS via the olfactory nerve.“ / Read more about concepts to breach the the blood-brain barrier - Quote in german only /
This explains the idea to administer the BeBot via nasal spray or inhaler. We believe that this form of administration is less invasive and easy to apply for everyone. But how do we get a BeBot in the size of DNA?
HOW PARASITES WORK INSIDE THEIR HOSTS
Parasites infest their host by using their host’s behavioural pattern. As a result, parasites even gain access to their host’s brain and neural tracts. Access is easier in invertebrates than vertebrates; as the latter have a blood-brain barrier. Some parasites (e.g. toxoplasma) and substances (e.g. morphine, codeine, heroine), however, are able to pass it.
One example would be Toxoplasma gondii: „Mice infested by Toxoplasma gondii lose their fear of cats and, consequently, fall an easy prey. Mice, therefore, function as intermediate hosts, whereas cats serve as definitive hosts. Inside the mouse Toxoplasma gondii remain in muscles and brain. Once inside the cat, these protozoa reproduce solely in the intestinal tract. …. other intermediate hosts among vertebrates are humans, for example. The acute infection is called toxoplasmosis.“ / (Florian Rötzer, Telepolis by Jaroslav Flegr: Toxoplasama, behaviour-altering parasite) Quote in german only /
BLOOD BRAIN BARRIER
In detail: The blood–brain barrier is a highly selective permeability barrier in the brain and spinal cord that separates the circulating blood from the brain extracellular fluid in the central nervous system (CNS) and maintains the homeostasis. The blood–brain barrier allows the passage of metabolic products as well as of nutrients crucial to neural function. The blood–brain barrier effectively protects the brain from many bacterial infections by preventing the entry of potential neurotoxins and germs. In its neuroprotective role, the blood–brain barrier hampers the delivery of many potentially important diagnostic and therapeutic agents to the brain and thereby constitutes a challenge to the treatment of most brain disorders.
This project is part of Sparks, a H2020 project funded by the European Commission
Credits and Special Thanks to
Christian Kittner - Inhaler Design / Elisabeth Leuthner - Logo and Graphic Design / Werner Pötzelberger - nanobots character design and 3D realization / Christopher Lindinger - futurelab / Claudia Schnugg - futurelab / Markus Scholl - futurelab